Targeting The Ercc1/xpf Nuclease For Cancer Therapy

Anticancer Therapy Targeting Telomeres And Telomerase
Anticancer Therapy Targeting Telomeres and Telomerase Current Status cancer cells cope with this by upregulating the active form of telomerase. the Artemis-related nuclease, Apollo,[4,5] and possibly also ... Fetch Document

SF424(R&R) Biographical Sketch Format Page
Rational, biology-based combination therapy for the treatment of ovarian cancer: Targeting XPA . The goal of this pilot project is to develop small molecule inhibitors of the xeroderma pigmentosum group A Targeting the ERCC1/XPF nuclease for cancer therapy . ... Get Content Here

Nucleotide Excision Repair Inhibitors: Still A Long Way To Go
The ERCC1-XPF nuclease was not recruited to the damaged DNA sites after ex druggable targets and no one in the past thought of regulating NER as a way to improve cancer therapy. Nucleotide Excision Repair Inhibitors: Still a Long Way to Go http://dx.doi.org/10.5772/46014 577. ... Doc Retrieval

Scientific Program 11-11-2014 (final Program Formatted)
Scientific Program . Organizing Committee Organizers Alan Tomkinson University of New Mexico, USA Vilhelm A. Bohr National Institute on Aging, USA Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA 11:50 DNA damage recognition and signaling ... Retrieve Full Source

CURRICULUM VITAE John J. Turchi - Indiana University
CURRICULUM VITAE John J. Turchi . PRESENT ADDRESS: Targeting the ERCC1/XPF nuclease for cancer therapy . Project Period: 09/26/2012 Annual conference of targeted lung cancer therapy ISLAC, Targeting NER in cancer Chemotherapy, 2007 Santa Monica CA . Lehman, ... Fetch Full Source

Structure, Vol. 13, 1849–1858, December, 2005, ª2005 Elsevier ...
Teins responsible for ERCC1/XPF complex formation. Both domains exhibit the double helix-hairpin-helix we propose a model for the targeting of XPF nuclease via ERCC1-mediated interactions in an extreme risk of UV-induced skin cancer and many features of accelerated ageing, respectively ... Document Retrieval